how can we detect genetic deficiency from in uterus or from environment? Can you qualify the term environment? Are you including physical or emotional factors?
annacai autoimmune said:
When you discuss genetics you must also discuss "epigenetics." That is how things like the environment, stress, and nutrition impact the expression of genes. Often this happens in the womb. It helps to explain why some members of the family don't have the disease. It also helps to understand that genes are not destiny. I am writing that thesis on vitamin D. The hormone that we call vitamin D switches on and off more than 200 genes. The researchers believe that much chronic illness later in life is caused by epigenetic factors en utero.
Thanks for sharing the link. I watched the video and participated in the cell activity. Interesting when I turned the control high, signaling high stress levels, the cell glowed and the epigenome activity increased by tightly winding itself. Then when I turned the knob down, signaling less stress, the genes loosened and the cell went dark.
annacai autoimmune said:
When you discuss genetics you must also discuss "epigenetics." That is how things like the environment, stress, and nutrition impact the expression of genes. Often this happens in the womb. It helps to explain why some members of the family don't have the disease. It also helps to understand that genes are not destiny. I am writing that thesis on vitamin D. The hormone that we call vitamin D switches on and off more than 200 genes. The researchers believe that much chronic illness later in life is caused by epigenetic factors en utero.
This has happened to me, my rheumatologist said the chest pain is the lining around my lungs enflamed and when it feels like my heart is being squeezed it is the lining around my heart. There is also numbness/tingling in my extremeties, my left morso than right, neurological difficulties are common as well for me, like a computer freeze as you put it, an example of this would be walking down the stairs then suddenly needing to grab the railing because my legs forgot how to move in mid step, or doing an activity that I have been doing for years and forgetting some steps suddenly. I’m sure we are not the only ones and I am glad we can share experiences like this.
Thanks for your input James. I believe the more infor we share the more likely it is that new patterns will emerge; if we see the pattern for the disease, maybe we can envision a cure too.
One thing is certain, I feel so much better knowing I am not alone in this.
Thanks for the information James and Janice. I need to know this too. Last night I felt as though I would have to go to ER because my face felt swollen and stretched and my eyes were red and very dry, this is the sjoren's, but the feeling of my skin stretching was scary.
yeah, sounds like it—were you swelling? are you now? how do you feel?
Unshoreandscared said:
Thanks for the information James and Janice. I need to know this too. Last night I felt as though I would have to go to ER because my face felt swollen and stretched and my eyes were red and very dry, this is the sjoren's, but the feeling of my skin stretching was scary.
Now, I am fine, my face is a little sore, but has resumed its normal shape. I am not sure should I go to the doctor’s tommorrow, my appointment is on Thursday.
Good information for me to know. Thank you. Lupus correlates to seasons and allergies. Very interesting.
I went through a period of time when I could not go to restaurants because I would cough so badly that I would produce sputum. That time is no longer, since starting the medication (or the time of year is changing)
Hey Janice, I just wanted to reply to your comment about not being able to move. I have had that experience in the hospital once, it scared the hell out of me. I was in for a blood transfusion and I was lying in bed and all of a sudden the nurse came in and she called my name. I could hear her, but I could not move or respond in any way for about five minutes, I was still breathing and my eyes was open, but for the life of me I just could not respond in any way. When I finally came around they were asking me what happened, and I was like I heard you but I could not respond. I am gonna mention that to my doctor as well. Get back with you later.
yeah..it was scary and sounds exactly like what happened to me . let me know what the doc says if you don't mind..i figure if we are all sharing info we may stumble upon valuable info.
Hay Corrina, don't feel bad this happens to me somedays through the week and my kids Just look at me then at each other and say , "She haveing on of those confused moments " , and we all LAUGH !!! If it wasn't for them i think my PHSCH doctor would have put me back in the ward !!! seriously . THIS GOT VERY BAD AT ONE POINT OF TIME . My 2 older kids( i have 3) , would get so upset with me haveing to repeat things over and over til they starting going to the PSCH doctor with me ... LOL . They would let the doctor know how things were taking place and she told them ,"that short term memory was what was happening and that it will come and go" , so now they ( we) just look at one another and laugh when they see this happening - it's really funny now !!! But feel GOOD to laugh and cry all at the same time ... IT will be alright !!!!... Beverly L.
Corrina said:
Hey,
I have had a similar incident happen. I just become disorinentated and forget things and confused. Very strange. I have had several tests done, MRI, Spinal tap, some type of electrodes on my scalp. There were of course no results that would indicate what this was from. It has happened a few times. I have had vision problems the last time, seeing spots, and tingling but no headache so I just contributed it to a migraine. I have no idea what causes this but neither do the doctors.