MGUS short for mono conol gammophy etc

I have recently had blood work and have been told my MGUS was very high. After 6 months of taking plaqenel it has not changed and was told needed to see a hemotologist/oncologist. Has anyone experienced this or know anything that they can share about this. Thanks

Purple, I too have MGUS along with my lupus. I have been seen by my oncologist for the past 2 years. Basically they just follow my blood work closely. The plaqunel was no help and after suffering with the side effects as long I could stand it I quit taking it and feel so much better without the side effects. I have a follow up with my hem/onc later this month, my rheumy says I will have to go on something for the lupus, but my WBC and platelets dropped so low I couldn't be started on Imuron. I wish I had a magic answer but I don't and to be honest the hem/onc or rheumy doesn't either. I understand how you feel, having even that 2-4% chance of multiple myeloma is scarey. I hopefully will know more after I see both the rheumy and hem/onc later in the month. Good luck to you and I look forward to hearing from you.

Monoclonal Gammopathy of Undetermined Significance... if you were to look it up online, you need the correct spelling. It resembles multiple myeloma, but mm only develops at a rate of 1-2% a year - and they do not know what causes this change. No symptoms, no problems, they don't recommend treatment - only monitoring. "Characterized by an accumulation of bone marrow plasma cells derived from a single abnormal clone", it is a common age-related problem. If they're telling you to see a specialist, it's because they see something more than just MGUS happening along with it that they need to keep an eye on, so you should go. It's only a small percentage that develop myoproliferative disorders. They just need to watch any changes to be sure there isn't more developing with you.

Thanks Tala for the reply. I let you know what they say. I have an appointment on the 21st.

Tala said:

Monoclonal Gammopathy of Undetermined Significance... if you were to look it up online, you need the correct spelling. It resembles multiple myeloma, but mm only develops at a rate of 1-2% a year - and they do not know what causes this change. No symptoms, no problems, they don't recommend treatment - only monitoring. "Characterized by an accumulation of bone marrow plasma cells derived from a single abnormal clone", it is a common age-related problem. If they're telling you to see a specialist, it's because they see something more than just MGUS happening along with it that they need to keep an eye on, so you should go. It's only a small percentage that develop myoproliferative disorders. They just need to watch any changes to be sure there isn't more developing with you.