Vit D and Autoimmune disease/month of birth study

This was posted by a friend online (Marilyn Morris) not sure if she is a member) Thought I'd share. (waving hi at Ann- hope you see this)

(TIME.com) -- The month in which babies are born can affect how their immune systems develop, and even how vulnerable they are to autoimmune diseases. Scientists studying the neurological disorder multiple sclerosis, in which the body's own immune cells destroy the protective coating around nerves and can lead to paralysis and loss of other functions, have long been puzzled by the "birth month effect." Many patients with MS are born in the spring, and rates of the disease are lowest for those born in November. Some have speculated that insufficient levels of vitamin D, which the skin produces when exposed to sunlight, on the mom's part could play a role, since babies born in May are gestated during the colder, darker months, while winter babies are in utero during the spring and summer. Now a study published in JAMA Neurology shows that this hunch may be correct, and suggests a mechanism for how the vitamin might be driving immune system development. TIME.com: Vitamin D not recommended post-menopause Researchers in the UK studied 50 babies born in London in May and 50 babies born in November between 2009 and 2010. They sampled blood from the newborns' umbilical chords and recorded levels of vitamin D and a specific type of immune cell known as autoreactive T-cells. T-cells are the white blood cells that battle pathogens like bacteria and viruses, but autoreactive T-cells are aberrant versions that mistake the body's own cells as foreign and attack them as they would an unwanted infection. TIME.com: Multiple Sclerosis drug may not slow disease The researchers found that babies born in May had vitamin D levels that were 20% lower than those in babies born in November, and almost double the amount of autoreactive T-cells. They speculate that vitamin D may be important in some way in educating T cells about how to recognize self cells; this occurs in the thymus, and errors in the training could lead to higher levels of the destructive T cells. The connection between vitamin D and immune disorders first emerged from population studies that showed people who lived further away from the equator, in places with less sunlight, were at higher risk of developing MS. But the researchers caution that their results still don't suggest that lower levels of the vitamin cause autoimmune disorders like MS. So it's not clear yet whether supplements of vitamin D could help to lower rates of the disease — especially for those conceived in July and born in May. In fact, experts continue to debate how much vitamin D is appropriate for otherwise healthy people when it comes to preventing disease, since studies on the subject are conflicting. The Institute of Medicine currently recommends that adults get about 600 IU daily. TIME.com: After Jack Osbourne's MS diagnosis More research is needed to figure out whether pregnant women might need to take more vitamin D in order to strengthen their babies' immune systems, but doctors now have a better understanding of what birth months have to do with how the immune system develops. This article was originally published on TIME.com © 2012 TIME, Inc. TIME is a registered trademark of Time Inc. Used with permission. Marilyn

Hi Julie,

Great post and Ann knowing such alot about this will give good feed back on it.

I just know i was born in August, sjogrens is going nuts with me as you know...Ann passed me on an excellent link from a friend and Vitamin D as alot to do with sjogrens besides...so when i do see my rheumo i either want to know if i've been tested or if i can be otherwise.

Terri :) xxx

Great article. My preemie was due in May (born in Feb) and they were nearly positive that he would have MS, although he does not. He is very intelligent, but has severe emotional issues. That said, my oldest (born in Nov) has rarely been sick a day and is healthy and most importantly emotionally one of those children (now adult) that everyone likes. I had no idea about the vitamin D although I took pre-natal vitamins with both. With my oldest I couldn't get enough fresh fruit, with the younger I could barely keep anything down. I wonder if that has anything to do with it as well. The inability of mother's to take in the proper nutrition during those months.

Thank you so much for posting this as I think it is important information to share with those we know and care about that may be expecting.

Again, thank you for this valuable information.

XXX,

DeAnne

wow!!! what a great article and discussion!!!

wow.

wow.

kangaroo waving good day smileyMate,

Julie i keep going you know me, stuck in the wheelchair again through another seizure hitting me harder but there's nothing we can do.

Well i am pleased your on the correct amount of vitamin D now, some doctors have'nt a clue but i need to see my rheumo and see if i've been tested on this as it's never been mentioned plus i want to know if i have Ataxia involvement besides asking to be tested for Lyme disease, been speaking with someone who's been diagnosed with it and apparently Lupus patients can have it without knowing and being with a good rheumo will boost my confidence in getting somewhere better now.

Love ya loads mate and you takecare :) xxx



jujubeee said:

How are you anyway Terri, double R one I?

You sound chipper in spite of! My first rheumie took me off Vit D supplements, who the heck knows why, but I continued anyway, and my new one prescribes me 50,000ui a week. At the time of my lupus dx in March 2010 my vit D was down to 3. LOL, my rheumie said it was the lowest he ever saw. Go figure.. I sure got plenty of Arizona desert sun!

It's now in normal levels. I'll go get Ann, I know she'd like this post.

Love Julie

Tez_20 said:

Hi Julie,

Great post and Ann knowing such alot about this will give good feed back on it.

I just know i was born in August, sjogrens is going nuts with me as you know...Ann passed me on an excellent link from a friend and Vitamin D as alot to do with sjogrens besides...so when i do see my rheumo i either want to know if i've been tested or if i can be otherwise.

Terri :) xxx